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Our top choices for Audrain County hotels

Exterior
Best Western Teal Lake Inn

Best Western Teal Lake Inn

Best Western Teal Lake Inn
2.5 star property
Mexico
8.4 out of 10, Very Good, (489)
"Very clean, well ran hotel"
United States
Leslie
$94 nightly
The price is $105
Jan 4 - Jan 5, 2026
Total with taxes and fees
Best Western Teal Lake Inn
Indoor pool
Capital O Amerihost Inn and Suites Mexico Hwy 54 MO

Capital O Amerihost Inn and Suites Mexico Hwy 54 MO

Capital O Amerihost Inn and Suites Mexico Hwy 54 MO
2.5 star property
Mexico
5.6 out of 10, (385)
"The room was decent. The staff was friendly. "
United States
Tiffany
$73 nightly
The price is $80
Jan 3 - Jan 4, 2026
Total with taxes and fees
Capital O Amerihost Inn and Suites Mexico Hwy 54 MO
Exterior
Days Inn by Wyndham Mexico

Days Inn by Wyndham Mexico

Days Inn by Wyndham Mexico
2.0 star property
Mexico
7.0 out of 10, Good, (297)
"Comfortable bed... Didn't like stool loose on base."
United States
Marvin
$77 nightly
The price is $86
Jan 1 - Jan 2, 2026
Total with taxes and fees
Days Inn by Wyndham Mexico
Reception
Budget Inn Mexico MO on US 54

Budget Inn Mexico MO on US 54

Budget Inn Mexico MO on US 54
2.0 star property
Mexico
7.0 out of 10, Good, (110)
"Great "
United States
Jedrzej
$85 nightly
The price is $95
Jan 2 - Jan 3, 2026
Total with taxes and fees
Budget Inn Mexico MO on US 54
Fridge, microwave, oven, stovetop
Rustic 2-bedroom cabin next to 1000+ acre Conservation area near Mark Twain Lake

Rustic 2-bedroom cabin next to 1000+ acre Conservation area near Mark Twain Lake

Rustic 2-bedroom cabin next to 1000+ acre Conservation area near Mark Twain Lake
2.0 star property
Paris
8.8 out of 10, Excellent, (5)
"The cabin was very clean and the Host was very nice and helpful."
United States
TREY
$238 nightly
The price is $238
Jan 2 - Jan 3, 2026
Total with taxes and fees
Rustic 2-bedroom cabin next to 1000+ acre Conservation area near Mark Twain Lake
House (1 Bedroom) | Interior
'grace Place' Clark House on Farm: Shared Hot Tub!

'grace Place' Clark House on Farm: Shared Hot Tub!

'grace Place' Clark House on Farm: Shared Hot Tub!
3.0 star property
Clark
10.0 out of 10, Exceptional, (2)
"Very clean with a wonderful country atmosphere. Perfect size for 1-2 people to share. The farm animals won my heart over!!!!!!!"
United States
Becky
'grace Place' Clark House on Farm: Shared Hot Tub!
Interior
Sisters Four Bed and Bath - Luxury living in a small town atmosphere!

Sisters Four Bed and Bath - Luxury living in a small town atmosphere!

Sisters Four Bed and Bath - Luxury living in a small town atmosphere!
Centralia
10.0 out of 10, Exceptional, (34)
"This was an awesome location! We enjoyed time on the back porch and was convenient to all the family events we attended!"
United States
Beth V.
Sisters Four Bed and Bath - Luxury living in a small town atmosphere!
House (2 Bedrooms) | Interior
Historic Clark Cabin w/ Deck & Fishing Pond Access

Historic Clark Cabin w/ Deck & Fishing Pond Access

Historic Clark Cabin w/ Deck & Fishing Pond Access
3.0 star property
Clark
Historic Clark Cabin w/ Deck & Fishing Pond Access
Apartment (2 Bedrooms) | Front of property
'kimberly's Hope' Clark Apt on Farm w/ Pool Access

'kimberly's Hope' Clark Apt on Farm w/ Pool Access

'kimberly's Hope' Clark Apt on Farm w/ Pool Access
3.0 star property
Clark
'kimberly's Hope' Clark Apt on Farm w/ Pool Access
Interior
Rut & Strut Ranch - 35 minutes from Mark Twain Lake! Quiet Cabin in the woods

Rut & Strut Ranch - 35 minutes from Mark Twain Lake! Quiet Cabin in the woods

Rut & Strut Ranch - 35 minutes from Mark Twain Lake! Quiet Cabin in the woods
Thompson
10.0 out of 10, Exceptional, (15)
"Nice cabin in quiet woods with a pond."
United States
Mary
Rut & Strut Ranch - 35 minutes from Mark Twain Lake! Quiet Cabin in the woods
Outdoor dining
Tastefully restored historic home in quaint town, 20 minute drive to Columbia MO

Tastefully restored historic home in quaint town, 20 minute drive to Columbia MO

Tastefully restored historic home in quaint town, 20 minute drive to Columbia MO
Centralia
10.0 out of 10, Exceptional, (154)
"Always wonderful staying at the Rollins House Inn! "
United States
Syndy D.
Tastefully restored historic home in quaint town, 20 minute drive to Columbia MO
Dining
Beautiful historic home in downtown Centralia, just 20 minutes from Columbia, MO

Beautiful historic home in downtown Centralia, just 20 minutes from Columbia, MO

Beautiful historic home in downtown Centralia, just 20 minutes from Columbia, MO
Centralia
10.0 out of 10, Exceptional, (45)
"It was our second time visiting the Sneed St house…and again it was lovely! "
United States
SHIRLEY F.
Beautiful historic home in downtown Centralia, just 20 minutes from Columbia, MO
Two double beds non smoking | Iron/ironing board, free WiFi, alarm clocks
America's Value Inn Mexico

America's Value Inn Mexico

America's Value Inn Mexico
1.5 star property
Mexico
5.4 out of 10, (19)
"who ever owns this property I met him ,seems to be very humble. He needs to update this property . i dont mind paying more if everything is well maintained and welcoming. "
United States
Sopan
America's Value Inn Mexico
Pool
Relax fish/play: Pvt 25-acre clear Blue Lake w/ home that sleeps 10 comfortably.

Relax fish/play: Pvt 25-acre clear Blue Lake w/ home that sleeps 10 comfortably.

Relax fish/play: Pvt 25-acre clear Blue Lake w/ home that sleeps 10 comfortably.
2.0 star property
Mexico
10.0 out of 10, Exceptional, (12)
"This was our 3rd stay, and it was amazing again! "
United States
Bert and Naomi W.
Relax fish/play: Pvt 25-acre clear Blue Lake w/ home that sleeps 10 comfortably.
House (3 Bedrooms) | Interior
Dog-friendly Cabin w/ Yard Near Auxvasse Creek!

Dog-friendly Cabin w/ Yard Near Auxvasse Creek!

Dog-friendly Cabin w/ Yard Near Auxvasse Creek!
3.0 star property
Kingdom City
Dog-friendly Cabin w/ Yard Near Auxvasse Creek!
Dining
Retreat on the Creek: Home overlooking a backyard lake and the Auxvasse Creek

Retreat on the Creek: Home overlooking a backyard lake and the Auxvasse Creek

Retreat on the Creek: Home overlooking a backyard lake and the Auxvasse Creek
2.0 star property
Kingdom City
9.8 out of 10, Exceptional, (12)
"Beautiful location "
United States
Scott H.
Retreat on the Creek: Home overlooking a backyard lake and the Auxvasse Creek
Exterior
Two-House Private Country Retreat - 4 Bedrooms and 3.5 Baths

Two-House Private Country Retreat - 4 Bedrooms and 3.5 Baths

Two-House Private Country Retreat - 4 Bedrooms and 3.5 Baths
Auxvasse, MO
10.0 out of 10, Exceptional, (31)
"A wonderful visit - we stayed here prior for an event and plan on doing so again, what a lovely place toAccommodate everyone as well as stocked with basics which means a lot for a small trip!"
United States
Alissa E.
Two-House Private Country Retreat - 4 Bedrooms and 3.5 Baths
Microwave, dishwasher, coffee/tea maker, toaster
Dog-Friendly Cabin w/ Yard Near Auxvasse Creek!

Dog-Friendly Cabin w/ Yard Near Auxvasse Creek!

Dog-Friendly Cabin w/ Yard Near Auxvasse Creek!
2.0 star property
Kingdom City
Dog-Friendly Cabin w/ Yard Near Auxvasse Creek!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Audrain County Hotel Reviews

Best Western Plus Columbia Inn

Best Western Plus Columbia Inn

10/10 Excellent
"Staff was kind and courteous. Clean rooms."
Pamela 4-night trip
Posted 2 days ago
Best Western Plus Columbia Inn

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